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Cyspera Cysteamine 5% has become the mainstay of hiqroquinone free hyperpigmentation treatment

Hydroquinone has been used for decades as the gold standard for hyperpigmentation problems. Although still controversial, hydroquinone is known to have a reputation as a mutagenic and carcinogenic compound. Both of these compounds are melano-cytotoxic agents known to induce ochronosis. Meanwhile, non-hydroquinone compounds such as kojic acid, arbutin, azelaic acid, retinoids, and hydroxy acids show lower efficacy.

Significant improvements in melasma treatment
In 2015 the first double blind test was conducted; randomized clinical study in 50 melasma patients. 2 other clinical studies also confirmed the results.
British Journal of Dermatology of Dermatology

Significant response in patients resistant to Kligman’s formula
Melasma lesions almost disappeared and signs of skin thinning (atrophy) recovered after treatment with topical cysteamine.
Journal of Cosmetic Dermatology

The depigmentation effect is better than HQ 4%
Comparison of Cyspera vs HQ 4% in a randomized controlled trial.
Researchers concluded that Cyspera is an alternative to replace the use of 4% HQ.
Australasian Journal of Dermatology

More efficacious & tolerated by the skin than the Kligman formula
Comparison of Cyspera vs modified Kligman’s formula in a randomized clinical study of 50 melasma patients.
Skin Research and Technology

Remains effective with fewer complications compared to TXA mesotherapy
Comparison of Cyspera vs. Tranexamic acid mesotherapy in a randomized clinical study in 54 melasma patients.
Archives of Dermatological Research

81%

Patients who use Cyspera® products containing genuine Cysteamine experience real results: skin becomes evenly brighter naturally.

Initial use

After 4 weeks

After 12 weeks

Results of Cyspera® Cysteamine application 15 minutes per day.
Results vary for each person due to differences in skin conditions.
(Courtesy of @20skin_tw)

Hasil yang terlihat pada bercak coklat dalam jangka panjang

Before using Cyspera®

Results after 16 weeks

After 5 years

Prior to treatment with Cyspera®, subjects were under Kligman formula treatment for 3 years. When treatment with Cyspera® is carried out, treatment with the Kligman formula is stopped for full use of Cyspera®. After 5 years of using Cyspera®, use Cyspera® 2 times per week.

Results of PIH treatment on the body with combination treatment

Before using Cyspera®

Results after 8 weeks

After 5 years

Results after 4 months. Daily application of Cyspera® to pigmented marks on the upper arms
with RevLite® laser treatments every two months.
(© GEK Skin Center (Indonesia))

Hyperpigmentation treatment results on the body

Before using Cyspera®

After using Cyspera®

Results after 4 weeks. Cyspera® application daily
for 30 minutes on the feet. © Hao Skin (Taiwan)

Before using Cyspera®

After using Cyspera®

Results after 10 days. Cyspera® application daily for 30 minutes
on the pigmented mark on the elbow. (Singapore)

How to use Cyspera® Cysteamine

The use of Cyspera® Cysteamine can be adjusted to each user’s needs and routine. This activity can be done either in the morning or evening to give users flexibility.

Consult your skin condition with an official dermatologist/beautician so that your skin condition before using Cyspera® can be diagnosed correctly and your doctor can provide specific treatment recommendations with Cyspera® .

Cyspera usage phases:
Intensive: once per day, for 16 weeks
Treatment: once per day, twice per week

1. Use when the skin is rested

Do not wash your skin before using Cyspera®. If washing your face is necessary, wait one hour before using Cyspera®.

2. Use of Cyspera® Cysteamine

Apply a thin layer of Cyspera® to the skin. Leave it for
15 minutes. A mild warming or tingling sensation may occur and last up to 30 minutes.

For optimal results, daily use of a broad-spectrum sunscreen with SPF 30 or higher following use of Cyspera® Cysteamine is highly recommended.

Cyspera is nonphotosensitive. Cyspera®  can be used regardless of sunlight intensity and on any skin type.

3. Wash the skin gently

Wash the area of skin that has received treatment with Cyspera® with a gentle skin cleanser. Pat the area gently.

4. Use moisturizer

Apply moisturizer to maintain skin hydration during the day.

Scientists introduce new technology

Cysteamine
Isobionic-Amide Complex™

Cysteamine Isobionic-Amide Complex™ was the first agent discovered
which activates a powerful synergistic effect to brighten the skin.

New technology

Cysteamine Isobionic-Amide Complex™

Cysteamine + Isobionic-Amide
Isobionic-Amide Complex™ strengthens the effectiveness of Cysteamine pigment corrector
by inhibiting several steps in the melanogenesis pathway

Cysteamine + AHA
AHA stabilizes Cysteamine; which increases its permeability into the skin

Isobionic-Amide + AHA
AHA immediately reacts with Isobionic-Amide; which produces an instant pigment brightening effect

Cyspera Intensive System™ is clinically proven to quickly and effectively fight hyperpigmentation
without worrying about corticosteroids, retinoic acid, and hydroquinone.

RESULTS OF USING CYSPERA INTENSIVE SYSTEM™

Clinical Cases of Pigmentation Problems

MELASMA

Results of Cyspera Intensive System™ application after 8 weeks. 15 minutes of use per day. The real patient. (ENG)

MELASMA

1 hasil sebelum 8 minggu pemakaian Cyspera Intensive System™ 15 menit per hari
2 hasil setelah 8 minggu pemakaian Cyspera Intensive System™ 15 menit per hari

Results after 8 weeks. Cyspera Intensive System™ application 15 minutes per day.
Courtesy of Lesley Clark-Loeser, MD (US)

77%

Cyspera Intensive System™ users experience reduced hyperpigmentation in 4 weeks and skin becomes softer and more evenly bright

How to use Cyspera Intensive System™

APPLY 15 MINUTES PER DAY

Cyspera usage phases:
Intensive phase: Once per day, every day, for 16 weeks until desired results are achieved
Treatment phase: Once per day, twice per week

Consult your skin condition with an official dermatologist/aesthetician so that your skin condition before using Cyspera® can be diagnosed correctly and your doctor can provide specific treatment recommendations with Cyspera® .

For first time users, it is important to note that the skin will need to adjust to use of  Cyspera Intensive™. Initial use can be done for 5 minutes once a day first. After one week, increase exposure to 15 minutes or based on doctor’s advice and personal observation. If irritation occurs, stop use for a few days until the skin  recovers. Repeat use of Cyspera Intensive™ for 5 minutes. For optimal results, use of a broad spectrum sunscreen SPF 30 or greater after daily use of the Cyspera Intensive System™ is highly recommended.

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Ruko Prominence, Jl. Alam Sutera Boulevard
Blok 38D No. 35 Tangerang  Banten INDONESIA 15143

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logo indo cipta estetika

Ruko Prominence, Jl. Alam Sutera Boulevard
Blok 38D No. 35 Tangerang  Banten INDONESIA 15143